Facilities/Instrumentation
Architectural Rendering of new Building
The Department of Chemistry and Biochemistry at Montana State University understands the important roll of instrumentation in research and training. Our department is committed to providing students, faculty, and staff with the instruments they require to stay at the forefront of research. In the last year, we added to two new mass spectrometers to an already well equipped facility. The mass spectrometry and proteomics facility now boasts six instruments including nanoflow chip MS/MS, accurate mass TOF, MALDI-TOF, and GCMS. Proteomics is well supported, and in addition to the new mass spectrometers, a Typhoon scanner with Decyder software are available for the analysis of protein expression experiments.
Structural Biology is well represented in our department and both NMR and X-ray equipment are available. Chemists and Biochemists alike benefit from the excellent NMR Instrumentation; 600, 500, 300, and 250 MHz NMR spectrometers. These instruments are used in routine analysis of small molecules and also protein structural determination. The center for X-ray crystallography has both a small molecule service facility and a macromolecular X-ray program. The determination of protein structures is supported by 12 SGI workstations.
Computational chemistry is being served by a 64 processor Linux cluster with Intel 32-bit and 64-bit processors organized into 14 nodes. These nodes are equipped with the latest versions of a broad spectrum of molecular modeling and electronic structure calculation software, such as Gaussian, Jaguar, Amsterdam Density Functional, MOPAC2000, MacroModel, and Tinker. Intel and Portland Group compilers are available for software development.
The Department also boasts high frequency CW and pulsed EPR instrumentation, a dynamic light scattering instrument, an isothermal titration microcalorimeter, an ultrafast femtosecond laser system, 3 tunable high resolution Nd: YAG pumped pulsed dye laser systems, and a quartz crystal microbalance capable of monitoring dissipation. Investigations of high energy gas-phase and gas-surface molecular interaction are conducted using a molecular beam apparatus that was originally designed by Nobel Laureate, Y. T. Lee, for crossed-beam studies of elementary reaction dynamics, and is one of the premier machines in the world for this purpose. Employing a pulsed hyperthermal atomic-oxygen beam, produced by laser detonation of O2, a wide range of high energy reaction are conducted with this apparatus.
We have spectrometers for Raman, FTIR, fluorescence, CD/MCD, and X-ray photoelectron spectrometry. In addition the equipment housed in our department, campus microscopy capabilities include transmission electron microscopy (TEM), scanning electron microscopy with cryogenics (SEM), atomic force microscopy (AFM), confocal imaging, and laser micro dissection and capture.
Mass Spectrometry and Proteomics
NMR
X-ray Crystallography
Computational Chemistry
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