Contact Information

Office: Room 55

Lab: Room 46 

Chemistry and Biochemistry Building
P.O. Box 173400
Bozeman, MT 59717

Phone: 406 994 5414

Fax: 406 994 5407


Research Group Website


  • B.S. Oregon State University, Corvallis, Oregon
  • Ph.D. in Physical Chemistry, University of Washington, 1965
  • N.I.H. Postdoctoral Fellow, Cal Tech, 1966-68


Awards and Professional Activities

  • Wiley Award for Meritorious Research, 1990
  • Cox Award for Teaching and Scholarship, 1992
  • Phi Kappa Phi Anna Krueger Fridley Award for Distinguished Teaching, 1994

Callis Group Overview

Enzymes enormously accelerate the rates of chemical reactions over the rates of the same reactions in water (by 108-1015 fold), but the precise manner by which enzymes accomplish this in detail is still considered an open question.
We are making a seamless transition from obtaining a detailed understanding of how the intense internal electric fields in proteins profoundly affect the properties of tryptophan fluorescence, towards a better understanding and more detailed view of how enzymes attain their astronomical acceleration of biochemical reactions.
We are currently performing classical and quantum molecular dynamics computations on the active sites of many enzymes, with the goal of observing unbiased enzymatic reaction events.


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