Biochemistry, Biological Signaling Mechanisms and Global Proteomic Analysis
Office: Room251 Chemistry and Biochemistry Building
Lab: Room 244 Chemistry and Biochemistry Building
P.O. Box 173400
Bozeman, MT 59717
B.A., Carleton College, 1961; Ph.D., University of California at Berkeley, 1966; Postdoctoral, University of California, Berkeley, 1966-67; Postdoctoral, Massachusetts Institute of Technology, 1967-69.
· BCH 104RN THE BIOCHEMISTRY OF HEALTH FOR NON-SCIENCE MAJORS
· BCH 442 METABOLIC REGULATION
Awards and Professional Activities:
Helen Hay Whitney Postdoctoral Fellow, 1966-69; NATO International Travel Fellow, 1975-80; European Molecular Biology Organization Senior Fellow, 1981-83; Charles and Nora Wiley Award for Meritorious Research and Creativity, 1995; Sabbatical Fellowship to Harvard Medical School and MIT, 1996-97 and to the National Proteomics Center at the Medical College of Wisconsin 2003-4.
The Dratz lab uses global proteomics and metabolomics to investigate signaling networks in cells, animals and humans. We are applying proteomics and metabolic technology to finding new early warning diagnostics for type 2 diabetes, to better understand Alzheimer's Disease, the triggering mechanisms human epilepsy, and reprogramming of adult human cells into induced pluripotent stem cells (hiPSCs). We are developing new fluorescent reporters for measuring metabolite levels in living cells in real time, that show great promise for optimizing the hiPSC reprogramming process and thus increasing the practicality of regenerative medicine, promise to improve stem cell function in individual humans, and for providing new insights in many other states of health and disease . Prof. Dratz has a long standing interest in biochemical nutrition and is applying proteomic and metabolomic methods to gain deeper understanding of nutritional issues in human health and preventative medicine, in collaboration with researchers in Plant Sciences and Health and Human Developmetnt. We are also investigating the use of the volatile metabolites in human breath as non-invasive reporters of metabolic health.
Shipman M, Lubick K, Fouchard D, Gurram R, Grieco P, Jutila M,Dratz EA. Proteomic and Systems Biology Analysis of the Monocyte Response to Coxiella burnetii Infection. PLoS One. 2013 Aug 21;8(8):e69558.
Chemistry & Biochemistry
103 Chemistry and Biochemistry Building
PO Box 173400
Bozeman, MT 59717